Jewish General Hospital
Department of Medicine
Monday Medical Grand Rounds
*** Noon to 1 p.m. ***
Join the virtual Medical Grand Rounds on Microsoft Teams.
Hybrid Medical Grand Rounds are additionally in person at the Block amphitheatre, room B-106
The Medical Grand Rounds are an accredited group learning activity as defined by the Maintenance of Certification Program of the Royal College of Physicians and Surgeons of Canada.
Some Rounds were video recorded.
Medical Grand Rounds 2024-2025
April 28
(Virtual only)
The Future of Medicine
Pieter R. Cullis, PhD, FRSC, FRS, OBC, OC
Professor, Biochemistry and Molecular Biology
Faculty of Medicine
University of British Columbia
Educational Objectives:
- The role of proteomics in disease diagnosis
- The role and future of gene therapies
- The advancing role of personalized medicine
- Anti-ageing protocols
April 21
No Rounds – Easter Monday
April 14
No Rounds – Passover
April 7
What's New in Hepatitis B and D
Julian Hercun, MD
Hepatologist,
Liver Unit, CHUM
Adjunct clinical professor
Department of Medicine, Université de Montréal
Educational Objectives:
- Discuss the epidemiology of hepatitis B and D in Canada
- Recognize opportunities for screening and therapy initiation
- Review indications for hepatitis B prophylaxis
- Evaluate the potential impact of novel therapies for hepatitis B and D
March 31
Residents case presentation
I. Severe Hypophosphatemia and Hypocalcemia Following Intravenous Ferric Derisomaltose and Denosumab Administration
Justin Kritzinger, MD
Internal Medicine Resident (PGY2)
McGill University
Educational Objectives:
- Calcium and phosphorus homeostasis is tightly regulated via several hormones including PTH, FGF23, and 1,25D
- iFGF23 levels increase following FCM (and possibly repetitive FDM) administration, resulting in increased renal phosphate excretion and decreased 1,25D production
- Severe hypophosphatemia and hypocalcemia with the use of FDM and denosumab, respectively are rare
- Synergistic effects likely exist with concomitant administration that can result in severe electrolyte imbalances
- Routine monitoring and occasional temporary replacement can mitigate the clinical consequences of hypocalcemia and hypophosphatemia
II. Massively Destructive S. Anginosus Endocarditis of a Bicuspid Aortic Valve
Adriano Petrangelo, MD
Internal Medicine Resident (PGY3)
McGill University
Educational Objectives:
- Recognize the varied presentations of infective endocarditis
- Identify the possible complications of infective endocarditis
- Understand predisposing conditions to developing infective endocarditis
III. Crisis in the Cortex
Hajare Iraqi, MD
Internal Medicine Resident (PGY2)
McGill University
Educational Objectives:
- Recognize the clinical presentation of bilateral adrenal hemorrhage.
- Identify atypical sites of bleeding complications with direct-acting oral anticoagulants.
March 24
The Osteoporosis Care Gap
I. William Silverstein, MD, MSc FRCPC
Staff Physician, Division of General Internal Medicine,
Sunnybrook Health Sciences Centre
Teachable Moments Editor, JAMA Internal Medicine
Assistant Professor (Clinician in Quality/Innovation),
Department of Medicine and Institute of Health Policy
Management and Evaluation, University of Toronto
II. Steven Shadowitz, MD, MSc, FRCPC
Staff Physician, Division of General Internal Medicine,
Sunnybrook Health Sciences Centre
President, Canadian Society of Internal Medicine
Associate Professor, Department of Medicine,
University of Toronto
Educational Objectives:
- Define the osteoporosis care gap
- Quantify the incidence and burden of the osteoporosis care gap
- Describe a novel approach to improve prescribing rates of anti-osteoporosis treatments after fragility fracture
March 17
Schwartz Rounds
Challenging Interprofessional Conversations
Louise Miner, MD
Director of Professional Services, JGH
Kevin Hayes
Clinical Ethicist
Vasiliki Bessy Bitzas
Associate Director of Nursing
Palliative Care, JGH
Educational Objectives:
- Provide a sense of community
- Give voice to healthcare professionals
- Normalize compassion for the self and others
March 10
DVT Awareness Month
Antiplatelet + Anticoagulant Therapy: When Less is More
Geoffrey Barnes, MD, MSc
University of Michigan Cardiovascular Center
Educational Objectives:
- Select antithrombotic therapies for patients with VTE and acute coronary syndromes that balance thrombosis prevention and bleeding risk
- Evaluate the evidence supporting combination anticoagulation-antiplatelet therapy for patients with atrial fibrillation versus VTE
March 3
Advancing Early Diagnosis and Management of Interstitial Lung Disease (ILD) and Idiopathic Pulmonary Fibrosis (IPF): A Path to Better Patient Outcomes
Deborah Assayag, MD
Director, ILD clinic McGill University Health Center
Scientist, Research Institute McGill University Health Center
Associate Professor of Medicine, McGill University
Educational Objectives:
- Recognize the importance of early diagnosis of ILD /IPF
- Understand the benefits and limitations of ILD/IPF medications
- Develop a practical approach to management of ILD/IPF medications and their side effects
February 24
Thirty Years of BRCA1/2 Research - What Have We Learnt?
William D Foulkes, MD
Division Director of the Divisions of Medical Genetics,
Department of Specialized Medicine, JGH and MUHC
Chair, Dept of Human Genetics, McGill University
Educational Objectives:
- To appreciate the advances made, the challenges faced and the road ahead for clinical management of and research into hereditary breast and ovarian cancer.
February 17 – Virtual ONLY
Innovations in Hypertension Control
Remote Management of Hypertension, Renal Denervation, and New Methods of Cuffless BP Monitoring
Naomi D.L. Fisher, MD
Director, Hypertension Service & Hypertension Innovation
Division of Endocrinology, Diabetes and Hypertension
Brigham and Women’s Hospital
Associate Professor of Medicine
Harvard Medical School
Boston, MA
Educational Objectives:
- Implement a process for collecting and reviewing home blood pressure in patients with hypertension, optimizing digital remote methods.
- Review evidence for the safety and efficacy of renal denervation, and evaluate patients with uncontrolled hypertension to determine who may benefit from this procedure.
- Explain the potential benefits of cuffless BP monitoring.
February 10
Hypersensitivity to IV Iron
Jesse Schwartz, MD, MSc, MPH, FRCPC
Chief, Division of Allergy and Clinical Immunology, JGH
Educational Objectives:
- Be able to identify and manage hypersensitivity to IV Iron
- Develop an approach to hypersensitivity to IV Iron
February 3
Targeted Radionuclide Treatment in Prostate Cancer
Parvaneh Fallah, MD, FRCPC
Medical Oncologist, JGH
Assistant Professor, McGill University
Educational Objectives:
- Understand the mechanism of action, available data and recommendations regarding use of targeted Radionuclide treatment in Prostate Cancer
- Future directions in using targeted therapy in Oncology
January 27, postponed to February 10
Hypersensitivity to IV Iron
Jesse Schwartz, MD, MSc, MPH, FRCPC
Chief, Division of Allergy and Clinical Immunology
Jewish General Hospital
Educational Objectives:
- Be able to identify and manage hypersensitivity to IV Iron
- Develop an approach to hypersensitivity to IV Iron
January 20
Hybrid Medical Grand Rounds – Residents Case Presentation
The Curious Case of the Man Whose Abdomen Swelled Then Swelled Again
Jack Rudski, MD, CM
PGY-3 Internal Medicine, McGill University
Krish Bilimoria, MD
PGY-3 Internal Medicine, McGill University
David Ji, MD
PGY-3 Internal Medicine, McGill University
Yousef Sebzali, MD
PGY-3 Internal Medicine, McGill University
Educational objectives:
- To review an approach to ascites
- To diagnose multisystem inflammatory disorders
- To maintain strategies to avoid premature diagnostic closure
January 13
Annual Humanization of Care Awareness Program Rounds
Theory to Healing – Bridging Music Therapy and Therapeutic Practice
Patil Harboyan, D.M.A.
Samuel Minevich, M.A., M.T.A.
Educational Objectives:
- Understand the principles of music therapy and its role in supporting physical, emotional, and psychological well-being.
- Explore evidence-based applications of music therapy in medical settings, including its effects on pain, stress, and rehabilitation.
- Recognize how music can be integrated into patient care as part of a holistic approach.
December 23
No Rounds – Christmas Day
December 30
No Rounds – New Year’s Day
December 16
Health Equity and Peripheral Artery Disease
Sonia Anand, MD, PhD, FRCPc
Professor, Department of Medicine, McMaster University
Associate Member, Department of Clinical Epidemiology & Biostatistics
Director, Population Genomics Program
Canada Research Chair in Ethnic diversity and Cardiovascular Disease
Heart and Stroke Foundation / Michael G. DeGroote Chair in Population Health Research
Educational Objectives:
- Review the pathophysiology of atherothromboembolic disease and its prevalence in diverse populations.
- Evaluate clinical trial outcomes, including the efficacy and safety of antithrombotic therapies, with consideration of their applicability to at-risk populations.
- Analyze systemic barriers contributing to delays in PAD diagnosis and treatment among marginalized populations
- Discuss strategies to optimize PAD management by addressing systemic barriers, promoting equitable access to therapies, and tailoring interventions to improve outcomes
December 9
It’s Not Always About the Arteries!
Jeffrey Minuk, MD
Chief, Division of Neurology, JGH
Educational Objectives:
- To review cerebral venous anatomy
- To review the clinical features and management of cerebral venous sinus thrombosis
December 2
The Current and Future Role of Cytopathology in Modern Medical Practice
Mauro Saieg, MD, PhD, FIAC
Associate Professor
Department of Pathology
Jewish General Hospital, McGill University
Educational Objectives:
- To understand the scope of diagnosis and organs/systems currently targetable by cytopathology practice
- To acknowledge the systems and classification schemes for cytopathology practice
- To understand the current role of AI in cytopathological practice and future perspectives of applications
November 25
"Measure Twice Cut Once": Risk Stratification of Thyroid Nodules
Michael Tamilia, MD, FRCPC
Director of Thyroid Center – JGH
Associate Professor of Medicine- McGill University
Educational Objectives:
- Elucidate Thyroid investigations.
- Explore importance of indeterminants cytology.
- Review molecular risk growth for improved stratification.
November 18
Automation and AI in Microbiology: Rise of the Machines
Gerasimos J. Zaharatos, MD, FRCP(C)
Divisions of Infectious Diseases & Medical Microbiology,
Jewish General Hospital
Chief, Division of Medical Microbiology,
Jewish General Hospital & Department of Clinical Laboratory Medicine (Optilab-MUHC)
Associate Professor of Medicine, McGill University
Educational Objectives:
- Review the technologic innovations introduced to medical microbiology laboratories in the last decade.
- Describe the expected impact of automation and artificial intelligence (AI) on the medical microbiology laboratory.
- Explain the potential ramifications of microbiology lab automation and AI on patient care.
November 11
Leading Transformational Change: The Hospital@Home Program
Alla'a Ali, MPH,
Manager of the Virtual Care Transformation Team, DQTEVE&SV
Lawrence Rudski, MD, FRCPC FACC FASE,
Director, Division of Cardiology & Azrieli Heart Center,
Medical Lead of Virtual Care
Erin Cook, MSN,
Director of Quality, Transformation, Evaluation,
Value, Clinical & Organizational Ethics, and Virtual Care
Educational Objectives:
- Understanding the Principles of Change Leadership: Participants will be able to describe the core principles of change leadership and how they can be applied in healthcare
- Recognizing the Impact of the Home at Home (H@H) Program: Attendees will explore the outcomes and implications of the H@H program on patient care and healthcare delivery
- Learning Change Leadership in Physician Led Interventions: Participants will gain insight into specific interventions that effectively enhance physician participation in the H@H program and their potential impact on program success
November 4
Advances in the Management of Acute Myeloid Leukemia in 2024
Alexandre Bazinet, MDCM, MSc
Assistant Professor, MD Anderson Cancer Center
Houston TX, USA
Educational Objectives:
- Understand the molecular heterogeneity of acute myeloid leukemia and how this knowledge is increasingly being used to tailor therapies
- Describe the evolution in the treatment of acute myeloid leukemia from a previous “one-size-fits-all” approach to a patient and molecularly-guided approach consisting of chemotherapeutic agents plus targeted agents
October 28
Quality & Risk Management Program
Fostering a Culture of Patient Safety: The Critical Role of Incident Reporting and Incident and Accident Management - Why Everybody’s Involvement Matters
Suzanne Levitz, MD
Associate Director of Professional Services, CCOMTL
Floriane Carole Rukundo, MPH,
Quality, Risk Management and Patient Experience Advisor, CCOMTL
Pierre-Jacques Deblois, MHA,
Quality, Risk Management and Patient Experience Advisor, CCOMTL
Educational Objectives:
- To understand the role, importance and requirements of incident and accident reporting in patient safety.
- To understand the management and disclosure process of patient safety incidents/accidents.
- To promote a culture of accountability, patient safety and continuous quality improvement.
October 21
Resistant Hypertension and the New Kids on the Hypertension Block: Novel Agents with New Mechanisms of Action
Ernesto L. Schiffrin, C.M., MD, PhD, FRSC, FRCPC, FACP
Distinguished James McGill Professor, Department of Medicine, McGill University,
Director, Hypertension and Vascular Research Unit, Lady Davis Institute for Medical Research,
Director, Cardiovascular Prevention Centre, Physician-in-Chief Emeritus, JGH
Educational Objectives:
- Attendees will learn approaches to resistant hypertension
- They will be appraised of the novel drugs for treatment of hypertension that have been developed with new mechanisms of action
October 14
No Rounds – Thanksgiving Day
October 7
Empowering Oncology through Geriatric Expertise: Why Comprehensive Assessments Matter
Professor Pierre Soubeyran, MD, PhD.
Medical Oncologist at Institut Bergonié, Comprehensive Cancer Center,
Professor of Medical Oncology at the University of Bordeaux, France
Miruna Anohim, MD, FRCPC
Geriatric Medicine, Jewish General Hospital
Erika Martinez B.SC. N CON (C)
Oncology Pivot Nurse – Breast Cancer, Jewish General Hospital
Educational Objectives:
- To explore the impact of frailty on cancer outcomes and provide practical tools for frailty screening in oncology
- To recognize the benefits of geriatric assessment and interventions in the field of oncology
- To compare multidisciplinary models that foster collaboration between oncology and geriatrics
September 30
Thoracic surgery for the internist
Mathieu Rousseau, MD FRCSC
Program Director, Advanced Thoracic and Upper GI Surgical Oncology Fellowship
Assistant Professor of Surgery, McGill University
Attending Surgeon, Division of Thoracic and Upper Gastrointestinal Surgery, McGill University Health Centre
Educational Objectives:
- Review the role of thoracic surgical procedures for internal medicine problems
- Learn about modern enhanced-recovery principles as applied to thoracic surgical pathologies
September 23
Repurposing Old Drugs for New Indications: The Good, the Bad and the Ugly
Samy Suissa, PhD, FRSC, FCAHS
Distinguished James McGill Professor of Epidemiology,
Biostatistics and Medicine, McGill University
Director, Centre for Clinical Epidemiology
Lady Davis Research Institute - Jewish General Hospital
Educational Objectives:
- Review some recent examples: statins, metformin, allopurinol, etc…
- Understand time-related biases in observational studies
- Introduce novel study designs with applications to drug repurposing
September 16
SIM ONE, DO ONE, TEACH ONE: Balancing Patient Care & Cardiology Training in the Cardiovascular Intensive Care Unit
I. Maria Fadous, MD, MHPE, FRCPC
Assistant Professor of Medicine, McGill University
Medical Director, Simulation - Division of Cardiology, JGH
II. Maude Peretz-Larochelle, MDCM, FRCPC
Assistant Professor of Medicine, McGill University
Co-Program Director, Adult Cardiology Residency Program, McGill University
Educational Objectives:
- Understand the role of simulation-based medical education in cardiology
- Identify key applications and benefits of simulation-based training
- Describe the challenges and limitations in implementing a simulation-based curriculum
- Discuss the role of interdisciplinary simulation and its impact on improving collaboration and communication among healthcare teams
- Explore future trends and innovations in simulation